The affective, psychological and physiological computing exploits the brain with up-to-the-minute innovative perspectives relating to information technology. Multidisciplinary science based on psychology, physiology and human affective processes is a grand challenge for computer science, cognitive neuroscience and biomedical engineering. The affective, psychological and physiological computing study can explain the mechanisms of emotion and cognition of mankind that support brains to execute the signals integration, multimodal modeling and inferential computing. New neuroimaging technologies like fMRI, PET, MEG, EEG and fNIRS, as well as from other sources, allow us to measure, model and mining the multiple forms of big brain data. This workshop addresses the computational, cognitive and biological perspectives of the affective phenomena, as well as topics relating to mental health and well-being to advance the understanding and application of psychological and physiological computing. The workshop will be co-located with the main conference BI 2017, November 16th, 2017 in Beijing, China.